Mission Bay Lecture Series
4:00 pm, MBay, Byers Auditorium (Genentech Hall)
"Transport Vesicle Biogenesis: Mechanism, Regulation, and Connections to Human Disease"
Randy Schekman, PhD
Professor, Dept. of Molecular and Cell Biology, UC-Berkeley; HHMI Investigator
Remote viewing: Parnassus N-217; Rock Hall 102.
My Vado HD video (a little shaky at the end)
[video vid_image=http://en.dogeno.us/wp-content/video/VID00129.png filename=/wp-content/video/VID00129.mp4 /]
Dr. Walter gave a 10-min introduction, which was really interesting. Dr. Schekman started the talk by showing a new PNAS TV advertisement. After that, he gave a brief introduction about what his lab found about the mechanism of COPII vesicle trafficking in yeast. He then moved into the mammalian study by showing electronic microscopy images of human patient fibroblasts having Sec23 mutation ...... In the end, he showed that these Sec23 mutation causes Vangl2 trafficking error.
Our lab studies membrane assembly, vesicular transport, and membrane fusion among organelles of the secretory pathway. Basic principles that emerged from our past and on-going studies in yeast are now being applied to studies of genetic diseases of protein transport.
Hi, great video of Shekman. He is a Faculty Member at Faculty of 1000 and I'd be interested to post this on our youtube channel (linked above). Do you have either a clip in compressed format you can send or I could convert the flash version with your permission.
Thanks,
Steve
Hi Steve, I don't have a edited version. You can convert the one in this post to your youtube channel.
Sir your simle diagram is interesting, for such diagrams not found in text books, it is good for we teacgers and students as well
Dear Prof. Kanthraj, the diagrams were from Randy's website.