Gö6976 / Go6976 (a PKC alpha-specific inhibitors; EXPERIMENTAL and MOLECULAR MEDICINE, Vol. 36, No. 2, 103-109, April 2004; Mol Biol Cell. 2001 Jul;12(7):1973-82.) {365250}
safingol (a PKC alpha-selective inhibitor, J Neuroendocrinol. 2003 May;15(5):508-15; Mol Biol Cell. 2001 Jul;12(7):1973-82) [D4681] {559300}
rottlerin (a PKC delta-selective inhibitor, J Neuroendocrinol. 2003 May;15(5):508-15) [R5648] {557370}
bisindolylmaleimide (Mol Cell Biol. 2002 Aug;22(16):5897-911)
A company called Calbiochem has a category about PKC inhibitors, which is available through this link.
There are many PKC inhibitor, however there is not special PKC-beta inhibitor. I need PKC-beta inhibitor,but I could not afford to buy it of Eli Lilly company. Can you help me?
By the way I want to know the price of Go6976 in Shanghai, China.
我查文献和公司目录没有看到很特异的PKC-beta的抑制剂,而且个人觉得没有一个抑制剂是特异的,最好还是用RNAi比较保险。我买Go6967大概是100左右,从sigma,不知道上海的情况。:)